Friday, January 3, 2014

After five sessions, the strength of neural connections was again close to normal cells that had be


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Researchers at the Centre for Health Science, University of Texas at Houston, United States, succeeded in reversing brain cells grown in laboratory methods of preserving food neuronal memory-related problems. The study represents the first step toward possible methods of preserving food treatments for memory loss associated with neurological diseases such as Alzheimer's.
MEET THE SEARCH Original title: Deficit in Long-Term Synaptic Plasticity Is Rescued by the computationally Predicted Stimulus Protocol Where was disclosed: Journal of Neuroscience Who did Rong-Yu Liu, Yili Zhang, Douglas A. Baxter, Paul Smolen, Leonard J. Cleary and John H. Byrne Institution: University of Texas, USA Result: Researchers serotonin added to the cell culture of sea-slug at irregular intervals, predicted by a mathematical model. Thus, they simulated methods of preserving food what would happen in an animal that was being trained to learn something brain. Thus, the connections between cells were restored. This means that, even with the memory problem created by the researchers, these cells were able to learn and use as much memory cells without any problem.
The study, published in the Journal of Neuroscience, was conducted with the brain cells of a type of slug Aplysia californica sea called that, despite having methods of preserving food a learning system and very simple memory, features similar to those of humans biochemical reactions.
The researchers found that as the various biochemical reactions that relate to memory have different speeds, the best way to deliver learning (and in this case, memory) is irregular intervals through training. Using a mathematical model, they could estimate the best time to "train" the cells grown in the laboratory.
"We have the habit of studying methods of preserving food at regular intervals, on Mondays methods of preserving food and Wednesdays, for example. Such research methods of preserving food shows that studying at irregular intervals may be better for learning," said John Byrne, lead author of the study, the site of SEE .
Memory Training - To determine if this strategy could help prevent memory loss, the authors methods of preserving food caused neuronal memory-related problems methods of preserving food in a culture of nerve cells of Aplysia methods of preserving food californica. They blocked the activity of a gene that produces a protein related to memory. This affected the intensity of the connections between neurons, which are responsible for long-term memory.
To mimic the training sessions, the researchers were adding serotonin methods of preserving food to the cell culture at irregular intervals, predicted by the mathematical model. Thus, they simulated what would happen in an animal that was being trained to learn something brain.
After five sessions, the strength of neural connections was again close to normal cells that had been affected. This means that, even with the memory problem created by the researchers, these cells were able to learn and use as much memory cells without any problem.
"This method can be applied to humans if we can identify methods of preserving food the same biochemical process. Our results suggest a new strategy for the treatment of cognitive impairments. Mathematical models can help develop therapies that combine the training and drug treatment," says Byrne . See also: Doctor explains how to enhance memory
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